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Fighting SIBO, I added these to the mix f herbals I'd been taking. I have to assume that InterFase was helpful, because I had better results after its addition than prior to it. On the other hand, it is possible that duration-of-use of the other herbals, or something else was at play. What I can say, base on "subject population of 1" being myself, is that herbals, including Oregano oil, Candibactins AR & BR, Allimax, and "Atrantil" used in combination & rotation with InterFase always included, proved more effective against SIBO-C than did Xifaxan. This is my second order of InterFase. The first wasn't "InterFase Plus" - but , figured I'd try it.