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I used the freeze treatment from the Doctor foot company and it didn't work at all and I maxed out the number of times they said I could use it on the same wart with NO RESPONSE whatsoever. I have used this Compound W before when I was younger and it worked great so I should have started with this again. It says to soak the area for 5 minutes, so I just apply after a shower at night. It's in a small tube and you just drip a drop on the top of the area you see the wart is in. Let it dry before you move on or you'll bump the cap of liquid off the wart and it won't have any affect. I used this for about a week and a half and I could tell the layers in the skin above the wart were starting to die off. Eventually the wart area comes closer to the surface and those layers shed as well until it's smooth. I'm not exactly sure about diagnosing this as a side affect, but I did feel a little bit sick while using this. Not like vomiting or achy or sore or stomach sickness, but just slightly off. I can't tell if that's a side affect of this, or just something else I was dealing with, but it was very coincidental. Anyone else have that feeling?