Bests & Worsts Reviews from Amazon

JUNE 2016 update. Inexplicably, the manufacturer (Interplexus) has replaced the main ingredient Phosphorylated Serine with Phosphatidyl Serine. It takes 10x the amount of the new ingredient to appreciably lower cortisol. The change is not being disclosed outwardly. ANY review of this product (including my own below) which was published prior to May 2016 is voided and should be disregarded because it would pertain to the previous ( and greatly EFFECTIVE) Seriphos and NOT the current (and completely INEFFECTIVE) version of Seriphos. I called Interplexus to complain about the removal of the effective ingredient (phosphorylated serine) and was given a whole bunch of off-topic gobbledygook in response. Finally the guy admitted that the new version does not help with sleep (i.e. high night-time cortisol) and that they were "working on it". Totally a lame response. Maybe someday they will come back with Seriphos "Classic", the original formulation for those who want a product that actually works. SO, don't buy this product based on the awesome reviews published before Spring 2016. That great product has been replaced with an "updated version" (an oxymoron if ever there was one) that does NOT WORK to lower cortisol. _____________________________________ Original Review, January 2016: I don't write many reviews, but this product has helped me immensely. Background: I'm a 55 year old male. I'm very athletic, lift weights, compete in multiple sports, spot-on diet, < 10% body fat. However, I was having issues waking up at 2-4am and having a hell of a time getting back to sleep. A blood test revealed morning cortisol at the very upper end of the "normal" range. Also, since high cortisol usually suppresses testosterone, my T was in the lower "normal" range, definitely not where I wanted it. Chronic high cortisol also causes higher fasting blood sugar, and mine had crept up to the mid 90's - way too high given my diet and athletic condition. Age is a factor with high cortisol as it tends to creep up as we get older. It is speculated that this causes many of the sleeping issues that older and elderly people have. Anyone thinking about purchasing Seriphos should absolutely read the following two articles before doing so: [...] [...] It is widely known that phosphatidyl serine will lower cortisol. Problem is that it takes a helluva lot of it (and it's expensive) because the body tends to strip the molecule apart during digestion making about 80% of what you take non bio-available. Seriphos solves this problem by being formulated to survive the first pass metabolism and making it into the bloodstream intact and bio-available. Results: I started right off by taking it at bedtime. Mistake.The first night this produced insomnia. Very discouraging. However, I took another dose in the mid morning, which produced no issues. So, for the first two weeks I took one dose AM and one dose in the mid afternoon before my weight workout. Gradually I moved the evening dose closer to bedtime. I could tell it was reducing my cortisol because I felt more relaxed and my morning fasted blood sugar was reducing back into the mid-70's, which is perfect. I was still having some early wake-up issues though. After about three weeks I finally had the nerve to try it again at bedtime. And this time- Voila'!!! - I slept like a baby. Now, after about 3 months, I take 1 dose AM and one dose before bed - with superb results. I go to bed at 10:30pm and wake up at 6:30am, frequently without moving a muscle all night. I may even stop the AM dose soon and just take it at night. I've read a couple of negative reviews from people whom Seriphos gave insomnia. Please read the above articles. This can happen - as it did with me - most likely from changes in neurotransmitter levels while your body adjusts. But once your body adjusts to the substance this should mitigate and produce results - as long as your problem is high cortisol. If your problem is not related to cortisol and is the result of a gaba deficiency or other neurotransmitter issues, Seriphos is not likely to help you. Read the second article I reference. I get the feeling a lot of people just buy "anti-anxiety" or insomnia products willy-nilly without a clue what their problem really is. Go get some blood work and do your homework if you want results. If your cortisol not elevated, there's no need to buy Seriphos. Bottom line: my cortisol has been significantly reduced, the scourge of the 3am wakeups is gone, I wake up feeling like a million bucks. And because the cortisol is lower my blood sugar has returned to excellent, and my testosterone level is back where I want it. Thanks for reading my review and good luck-